Erythropoietin enhanced recovery after peripheral nerve injury
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چکیده
منابع مشابه
Erythropoietin enhanced recovery after peripheral nerve injury
Peripheral nerve injuries are common disorders affecting the US population and represent a great economic and social burden. Acute injuries to peripheral nerves are most often due to an acute trauma or iatrogenic injury, with the resultant neurological deficit dependent on the injury type and severity. Clinical manifestations include a variable degree of motor and/or sensory deficits, with comp...
متن کاملErythropoietin promotes functional recovery and enhances nerve regeneration after peripheral nerve injury in rats.
BACKGROUND AND PURPOSE EPO has been shown to have beneficial effects in a variety of CNS injury models. The purpose of this study was to evaluate the effects of EPO on nerve regeneration and functional recovery in a rat model of peripheral nerve surgery. MATERIALS AND METHODS The sciatic nerve of the rat with a 10-mm defect was bridged with a silicone rubber tube. Forty adult male Sprague-Daw...
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Background: Valproic acid (VPA) is used to be an effective anti-epileptic drug and mood stabilizer. It has recently been demonstrated that VPA could promote neurite outgrowth, activate the extracellular signal regulated kinase pathway, and increases bcl-2 and growth cone-associated protein 43 levels in spinal cord. In the present research we demonstrate the effect of VPA on peripheral nerve r...
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ژورنال
عنوان ژورنال: Neural Regeneration Research
سال: 2017
ISSN: 1673-5374
DOI: 10.4103/1673-5374.213544